Radiopharmaceutical chemistry

  • Cyclotron opens up new prospects for fundamental & applied research in radiopharmaceutical chemistry

    PETtrace 700S cyclotron with closed radiation shield   photo/©: Stefan F. Sämmer, JGU

    New particle accelerator generating radioactive isotopes for use in nuclear chemistry will be employed to create new medical radiopharmaceuticals

  • Simple and Fast Method for Radiolabelling Antibodies against Breast Cancer

    Photoradiolabelling Using UV light, radiolabelled antibodies can be produced in just 15 minutes. Jason P. Holland, UZH

    Radioactive antibodies that target cancer cells are used for medical diagnostics with PET imaging or for targeted radioimmunotherapy. Researchers from the University of Zurich have created a new method for radiolabelling antibodies using UV light. In less than 15 minutes, the proteins are ready-to-use for cancer imaging or therapy. Radioactive antibodies are used in nuclear medicine as imaging agents for positron emission tomography (PET) – an imaging technique that improves cancer diagnosis and monitoring of chemotherapy. Radioactive drugs can also be designed to kill tumors by delivering a radioactive payload specifically to the cancer cells. This treatment is called targeted radioimmunotherapy.