Nanocapsules

  • Fighting Forgetfulness with Nanotechnology

    The international research team is working on a treatment on dementia like Alzheimer, which leads to a death of neuronal cells. © shutterstock.com/Naeblys

    About 29 million people around the world are affected by the disease "Alzheimer". In an international collaboration, scientists of the Max Planck Institute for Polymer Research (MPI-P) in Mainz together with teams from Italy, Great Britain, Belgium and the USA are now working together on an approach for a therapy. On the one hand, the goal is to understand the processes occurring in the brain that lead to the disease; on the other hand the development of a method for targeted drug delivery.

  • Nanocapsules Enable Cell-Inspired Metabolic Reactions

    Schematic illustration of the bio-catalytic nanocompartment with encapsulated enzyme phosphoglucomutase for the conversion of glucose-1-phosphate into the desired product glucose-6-phosphate. University of Basel

    Researchers at the University of Basel succeeded in developing capsules capable of producing the bio-molecule glucose-6-phosphate that plays an important role in metabolic processes. The researchers were able to produce the metabolite in conditions very similar to the biochemical reaction inside natural cells. The results have been published in the scientific journal Chemical Communications.

  • News About Drug Delivery

    As the loading with curcumin (yellow) increases, the dissolution rate of the containers made of polymeric micelles (blue) decreases. (Picture: Ann-Christin Pöppler)

    Nanocontainer for drugs can have their pitfalls: If they are too heavily loaded, they will only dissolve poorly. Why this happens is now reported by a Würzburg research group in "Angewandte Chemie". Nanocapsules and other containers can transport drugs through a patient's body directly to the origin of the disease and release them there in a controlled manner. Such sophisticated systems are occasionally used in cancer therapy. Because they work very specifically, they have fewer side effects than drugs that are distributed throughout the entire organism.

  • Peptides vs. superbugs

    An X-ray capillary that is being filled in order to analyze the nanostructure of the shuttle system. Empa

    Several peptides have an antibacterial effect - but they are broken down in the human body too quickly to exert this effect. Empa (Swiss Federal Laboratories for Materials Science and Technology) researchers have now succeeded in encasing peptides in a protective coat, which could prolong their life in the human body. This is an important breakthrough because peptides are considered to be a possible solution in the fight against antibiotic-resistant bacteria. They occur in many organisms and constitute natural weapons against bacteria in the body, being known as antimicrobial peptides.