Based on the proven MCR microarray analysis platform of the Munich-based GWK Präzisionstechnik GmbH scientists at the Technical University of Munich have developed a new microarray-based rapid test for SARS-CoV-2 antibodies. Sebsatian Kissel / TUM

During the continued progression of the Corona pandemic, rapid, inexpensive, and reliable tests will become increasingly important to determine whether people have the associated antibodies – either through infection or vaccination. Researchers at the Technical University of Munich (TUM) have now developed such a rapid antibody test. It provides the result in only eight minutes; the aim is to further reduce the process time to four minutes.
There are currently more than 20 different test procedures available for determining whether a person has antibodies against the new Corona virus. The waiting times for the results range between ten minutes and two and a half hours.

 

 

COVID pandemic fast-tracks technological development that will clean plastic litter in oceans. The current COVID pandemic challenges our societies with extensive amounts of plastic mask debris released into our environment. As a response to this growing issue, and to respond to the nanoparticle pollution in the water ecosystems, several technological solutions are being accelerated to achieve the overall goal – a cleaner, safer and healthier environment for everyone. InNoPlastic, a newly launched EU H2020 research and innovation project, combines ultra-sound methodologies with other innovative solutions, to tackle plastic litter and enable easier removal from oceans and the seas worldwide.

A comparison of different light microscopy techniques: STED (bottom left) improves the sharpness of detail drastically compared to conventional confocal microscopy (top left). MINSTED (right) achieves a resolution that is yet ten times higher. © Michael Weber / Max Planck Institute for Biophysical Chemistry

Scientists working with Stefan Hell at the Max Planck Institute (MPI) for Biophysical Chemistry in Göttingen and the Heidelberg-based MPI for Medical Research have developed another light microscopy method, called MINSTED, which resolves fluorescently labeled details with molecular sharpness. With MINSTED, Nobel laureate Hell has come full circle. “A good 20 years ago, we fundamentally broke the diffraction resolution limit of fluorescence microscopy with STED. Until then, that was considered impossible,” says Hell. “Back then we dreamed: With STED we want to become so good that one day we will be able to separate individual molecules that are only a few nanometers apart. Now we've succeeded.” At that time, the STED principle amounted to a revolution in light microscopy. For this conceptual leap and subsequent developments, Hell received the Nobel Prize in Chemistry in 2014.

The phantom used for hyperpolarized imaging, with an illustration of imaging slices acquired using the new technique. photo/©: Laurynas Dagys, University of Southampton

New technique using nuclear spin hyperpolarization of hydrogen paves the way for further advances in the field of MRI. Magnetic resonance imaging (MRI) is already widely used in medicine for diagnostic purposes. Hyperpolarized MRI is a more recent development and its research and application potential has yet to be fully explored. Researchers at Johannes Gutenberg University Mainz (JGU) and the Helmholtz Institute Mainz (HIM) have now unveiled a new technique for observing metabolic processes in the body. Their singlet-contrast MRI method employs easily-produced parahydrogen to track biochemical processes in real time. The results of their work have been published in Angewandte Chemie International Edition and chosen by the editors as a "hot paper", i.e., an important publication in a rapidly-developing and highly significant field.