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Project Magneto Hyperthermia
A novel approach in magneto hyperthermia gives hope to cancer patients
Magnetic nanoparticles transform electromagnetic energy from an external high-frequency field to heat. As a consequence, if magnetic nanoparticles are put inside a tumor and the patient is placed in an alternating magnetic field of well-chosen amplitude and frequency, only the tumor temperature rises. The elevation of temperature and change in pH may enhance tumor oxygenation and radio- and chemo sensitivity, thus shrinking tumors. The technique is also of great value in many other applications from drug-delivery in medicine to the polymer industry.
Numerous clinical trials worldwide have studied hyperthermia in combination with radiation therapy and/or chemotherapy. MagForce AG has received EU-wide regulatory approval for treatment of brain tumors. The benefits of the application of a Nano technological approach, as compared to conventional treatments, are expected to be accompanied improvement of the quality of life of the patients.
However, as any other therapy it has limitations. Especially the specific targeting of the cancer cell and the intensity in the increase of permeability should be increased. This is the focus of our research. Nanoscale Biomagnetics has developed a tailor-made equipment for us to test and develop a novel therapy on the basis of magneto hyperthermia for cell culture studies. Targeting is the center of our research.
As an independent small start-up company we need financial support to be able to give hope to patients. Thank you very much for your kindness.
Please contact me:
Chemist, toxicologist & nanotechnologist
Prof. human toxicology, University of Iowa, USA
Prof. emeritus nanotechnology / nano bio interface, University of Applied Sciences, Enschede, The Netherlands
Alumni Humboldt fellow