Brain

  • Molecule flash mob

    High PIP2 concentrations on the cell membrane (left) prohibit SERT oligomerisation or dissociation so the level of oligomerisation is fixed. The PIP2 concentration in the endoplasmic reticulum is very low (right). The SERT oligomerisation therefore strives for equilibrium. TU Wien

    Neurotransmitter transporters are some of the most popular transport proteins in research as they play a major role in the processing of signals in the brain. A joint study by TU Wien and the Medical University of Vienna has now successfully demonstrated for the first time the structural impact of membrane lipids on medically relevant serotonin transporters

  • Walking is bound hand and foot: How long projecting neurons couple the movement of our limbs

    Netzwerk menschlicher Neuronen.

    We humans walk with our feet. This is true, but not entirely. Walking, as part of locomotion, is a coordinated whole-body movement that involves both the arms and legs. Researchers at the Biozentrum of the University of Basel and the Friedrich Miescher Institute for Biomedical Research have identified different subpopulations of neurons in the spinal cord with long projections. Published in Neuron, the results show that these neurons coordinate movement of arms and legs and ensure a stable body posture during locomotion.